Salinomycin, a polyether ionophoric antibiotic, inhibits adipogenesis

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Cd(II) and Pb(II) complexes of the polyether ionophorous antibiotic salinomycin

BACKGROUND The natural polyether ionophorous antibiotics are used for the treatment of coccidiosis in poultry and ruminants. They are effective agents against infections caused by Gram-positive microorganisms. On the other hand, it was found that some of these compounds selectively bind lead(II) ions in in vivo experiments, despite so far no Pb(II)-containing compounds of defined composition ha...

متن کامل

Ionomycin, a new polyether antibiotic.

Ionomycin, a new polyether antibiotic with a high affinity for calcium ions, is obtained in pure form from fermentation broths of Streptomyces conglobatus sp. nov. Trejo by solvent extraction. It is unique amongst known polyether antibiotics in that it has a UV absorption maximum at 300 nm. thereby distinguishing it from other antibiotics of its class. The Ca salt has the molecular formula C41H...

متن کامل

Isolation of a new polyether antibiotic, lonomycin.

A new polyether antibiotic, lonomycin, was isolated from the culture of Streptomyces ribosidifcus strain TM-481. The antibiotic obtained as a sodium salt is a colorless prism having a molecular formula of C44H75O14Na(M.W. 850), m.p. 188 approximately 189 degrees C, and has no absorption maxima in the ultraviolet region. The infrared and NMR spectra of the antibiotic suggest the presence of a ca...

متن کامل

Epigrisorixin, a new polyether carboxylic antibiotic.

addition of methyl oleate (1%) to the original fermentation culture increased the antibiotic titer3). Under these conditions, three nigericin-type antibiotics were isolated, grisorixin (1) (unpublished data), abierixin3) and epinigericin4) (3). The comparative biological activity of the two epimeric antibiotics, nigericin and epinigericin on a protist Tetrahymena pyriformis GL5) and Bacillus ce...

متن کامل

Further proposals for polyether antibiotic notation.

The polyether antibiotics reported by the year 1968 were nigericin1) (X-4642)), lasalocid (X-537A2)), X-2062), dianemycin3) and monensin4). Monensin (1) was the only one whose structure was known at that time. In the following decade, the number of distinct polyethers increased from these five to forty-six, almost all of which were structurally assigned. As a result of this rapid growth, a numb...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Biochemical and Biophysical Research Communications

سال: 2012

ISSN: 0006-291X

DOI: 10.1016/j.bbrc.2012.10.080